University Eye Hospital Tübingen, Experimental Ophthalmology, Laboratory of Neurohistology and Cell Biology

Neurobiology of the retina

The Laboratory for Neurohistology and Cellular Biology deals with neuronal circuits, chemical messenger substances, and genes which are required for flawless transmission of signals in the retina. This research also provides a basis for developing preventive and therapeutic strategies of treatment for retinal processes of degeneration.

Eberhart Zrenner, Prof. Dr., Director of the University Eye Hospital
Konrad Kohler, Dr., Head of Laboratory

Röntgenweg 11
72076 Tübingen
Germany
Phone: +49-7071-298-5030
Fax: +49-7071-29-5777

The research interests of the Kohler lab are focused on the investigation of the structure of the neuronal network of the retina and the cellular mechanisms. Special topics of the research group are intoxication and side effects of drugs, degenerative processes in hereditary retinal diseases, expression of a local renin-angiotensin system in the eye, effects of growth factors and synaptic plasticity. The following techniques are established: immunocytochemistry, electron microscopy, immunoassays (RIA, ELISA), high pressure liquid chromatography (HPLC), in-situ hybridisation, qualitative and quantitative RT-PCR, retinal organ cultures.