Quark Biotech Inc
Drug discovery and development, genomics research
Quark is an evolving pharmaceutical company, based in Fermont, USA, using rational drug design for the development of new therapeutics for unmet medical needs.
Daniel Zurr, Ph.D., CEO
Rami Skaliter, Ph.D. COO
Shai Erlich, Ph.D., Chief Development Officer
Elena Feinstein, Ph.D., CSO
Philip B. Simon, Chairman
Joseph Rubinfeld, Ph.D., Vice Chairman
Steven B. Fink
Daniel Zurr, PhD
Tomomi Okamoto
Bruce Molitoris, MD
Patrick Murray, MD
Emil Paganini, MD
Lakhmir Chawla, MD
Ravindra L. Mehta, MD
Dganit Dinour, MD
Jayakrishna Ambati MD
Jason Slakter, MD
Philip J. Rosenfeld, MD, PhD
Ayala Pollack, MD
Anat Loewenstein, MD
Dov Weinberger, MD
Peter K. Kaiser, MD
6501 Dumbarton Circle
Fremont, CA 94555
USA
Phone: +1-510-402-4020
Fax: +1-510-402-4021
The company’s proprietary technology for gene discovery, BiFAR, is used to identify and target genes involved in serious diseases. The drugs under development belong to the class of siRNA drugs (RNA interference mechanism). The company’s drug pipeline also includes small molecule and antibody drug candidates.
Two siRNA drugs are ending phase I/IIa and entering full phase II sometime in 2007 - one for the treatment of age-related macular degeneration and one for the prevention of acute renal failure.
The following section contains a selection of the company’s most relevant patents. For comprehensive patent information please refer to the espacenet databases.
Related patents
- Method of Identifying Genes
- Sequences Characteristic of Hypoxia-Regulated Gene Transcription
- Isolation of cDNA Encoding for Secreted or Membranal Proteins
- Sequences Characteristic of Bladder Cancer
- Fas Pathway Genes
- ATM Mutations in Breast Cancer
- Genes Associated with Mechanical Stress, Expression Products Therefrom, and Uses Thereof
- Sequence Characteristics of Bladder Cancer
- Methods of Using Colony Stimulating Factors in the Treatment of Tissue Damage and Ischemia
- Prediction of Cancer by Detection of ATM Mutations
- Use of the Axl Receptor for Diagnosis and Treatment of Renal Disease
- 1Microarrays and Production Thereof
- Methods for Cloning Nucleic Acids in a Desired Orientation
- CTLA-2 and Uses Thereof
- Diagnosis and Treatment of Liver, Pulmonary and Cardiac Fibrosis
- Diagnosis and Treatment of Nephropathy
- Diagnosis and Treatment of Kidney Fibrosis and Other Fibrotic Diseases
- Inversion-duplication Nucleic Acids and Libraries Prepared Therby
- Gene and Polypeptide which Opposes the fas Pathyway
- Sequences Characteristic of Hypoxia-regulated Gene Transcription
- Recombinant Antibodies Against CD55 and CD59 and Uses of Thereof
- Oligoribonucleotides and Methods of Use Therof for Treatment of Fibrotic Conditions and Other Diseases
- Mechanical Stress Induced Genes, Expression Product Therefrom, and Use Thereof
- Therapeutic Modulation of the fas Pathway
- Oligoribonucleotides and Methods of Use Thereof for Treatment of Fibrotic Conditions and Other Diseases
- Oligoribonucleotides and Methods of Use Thereof for Treatment of Cardiovascular Diseases
- Use of the Endo-180 Gene and Polypeptide for Diagnosis and Treatment
- Therapeutic Uses of Inhibitors of RTP801
- Oligoribonucleotides and Methods of Use Thereof for Treatment of Alopecia, Acute Renal Failure and Other Diseases
- Novel Tandem siRNA
- Gene Identification Method
- Hypoxia-regulated Genes
- Hypoxia Regulated Genes
- Isolation of cDNA Encoding for Secreted or Membranal Proteins
- Hypoxia-regulated Genes
- Sequence-dependent Gene Sorting Techniques
- Hypoxia-regulated genes
- Method for Enrichment of Natural Antisense Messenger RNA
- Selection subtraction approach to gene identification
- Mechanical Stress Induced Genes, Expression Products Therefrom, and Uses Thereof.
- Hypoxia Regulated Genes
- Method for Enrichment of Natural Antisense Messenger RNA
- Hypoxia-regulated Genes
- Hypoxia-regulated Genes
- Genes Associated with Mechanical Stress, Expression Products Therefrom, and Uses Thereof
- Hypoxia Regulated Genes
- Hypoxia-regulated Genes
- Use of Endo180 Receptor for Diagnosis and Treatment of Disease
- Methods of Diagnosing Bladder Cancer
- Therapeutic Uses of Inhibitors of RTP801
- The 76a11 Polypeptide and Uses Thereof
- Systems and Methods for Variable Trapping